For example, in every prostate carcinoma, cancer cells are found outside the “prostate capsule” (which actually does not exist, but only represents the outer layers of the organ) and in the blood. Unfortunately human biology is not that simple: with every cancerous disease, cancer cells and th eir secretions and their micro vesicles are spread all over the body. The idea behind the radical lymphadenectomy is this: if the primary tumor and the infected lymph nodes are removed from the body, the cancer is also completely removed and the disease is healed. The additional information gained is offset by massive side effects. While you get a realistic diagnostic value by getting more precise information about the affected lymph nodes compared to non-invasive methods (like MRT and PET), there still is a discussion about the true survival benefit of lymph node removal. Most of these are performed within the prostate surgery (prostatectomy). The radical surgical removal of the lymph nodes, also called lymphadenectomy, is still a standard method in prostate cancer. When and how should (possibly) affected lymph nodes be treated or removed? 2Ĭase 1: The prostate itself has not yet been treated. Illustration 2: The remodulation of lymphatic vessels, which pre-drives the metastasis in cancer. Usually they are detected either by modern imaging techniques or by the histological analysis of the lymph nodes themselves, when removed prophylactically during a surgery. Lymph node metastases are the scattered cancer cells in lymph nodes (metastasization). In this system the lymph nodes are the stations, where the lymph is filtered. In the lymph system, instead of blood, lymph fluid (called lymph) is transported. Lymph nodes are up to one centimeter large, bean-shaped organs, which are interlinked and connected to the so-called lymphatic system. What are lymph nodes and lymph node metastases? With NanoKnife, there now is the possibility for high-precision and minimally invasive treatment of lymph node metastases without radiation or surgery. Targeted radiation therapies can be an alternative, but these therapies severely restrict the options of follow-up treatments, which are unfortunately often necessary in case of scattered cancer. The standard treatment is the surgical removal of all pelvic lymph nodes, which is a substantial intervention. ![]() Prostate cancer often spreads into the surrounding lymph nodes. Targeted and gentle removal of affected lymph nodes without irradiation or surgery
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